Posts Tagged ‘GSK’

South Africa Signs On To New Patent Pool For Neglected Tropical Diseases

May 7th, 2010

The South African government will work to end the neglect of neglected tropical diseases by using a new patent pool to develop drugs for more than a dozen diseases.  South Africa is the first country to take action and recognize the tremendous potential that the patent pool could have.  The patent pool was created by GlaxoSmithKline and includes over 2,300 patents that will aid in the drug development process to create drugs to treat neglected tropical diseases, TB, malaria and others.  The impacts of these diseases are enormous as they cause adverse health effects and even death for millions each year.  While numerous pharmaceutical companies have generously donated drugs to treat neglected tropical diseases, new drug development has basically stalled as the poorest regions of the world lack market incentives for drug creation because the population is too poor to buy the drugs.    

The new patent pool will target the 50 least developed nations worldwide, a majority of which are in Africa, to encourage innovation in drug development.  One of the most remarkable aspects of the patent pool is not only does it provide access to promising compounds that can be used for drug development, it also will provide expertise and technical knowledge to aid in the process.  We are optimistic that this new patent pool will promote innovation and collaboration to make significant strides in the fight against neglected tropical diseases.

Reading List – 3/9/2010

March 9th, 2010

Hello everybody! Today we’re reading about GlaxoSmithKline upping its efforts to fight lymphatic filariasis, a new treatment for American soldiers who caught cutaneous leishmaniasis in Iraq, the latest release on the fight against LF in India, and, on a different note, a group of ultra-Orthodox rabbis declaring that lox should no longer be considered kosher due to a variant of roundworm found in fish.

In tough climate, GSK dedicates plant to fight elephantiasis, Rick Smith, Localtechwire

Heat therapy shown effective in treating cutaneous leishmaniasis among US soldiers in Iraq, PLoS Neglected Tropical Diseases

DMO allays fears over DEC tablets, The Hindu

Rabbis Claim Lox No Longer Kosher, Erica Butler, NBC New York

Reading List 2/3/10

February 3rd, 2010

Today we’re reading about the fallout from Monday’s unveiling of the fiscal year 2011 budget and various analysis of how it will impact the global health sector and NTDs in particular. We’re also reading about other miscellaneous developments in NTDs and global health.

  1. Obama’s FY 2011 budget gives global health funding boost, Kaiser Family Foundation
    An article breaking down global health spending in the fiscal year 2011 budget.
  2. Aid advocates happy, not thrilled with Obama’s new budget, Josh Rogin, Foreign Policy
  3. Obama’s Global Health Budget a Mixed Bag, Te-Ping Chen, Change.org
    Two different analysis of the global health aspect of the 2011 budget.
  4. Glaxo CEO: Time to diversify, help poor countries, Associated Press
    An interview with the CEO of GlaxoSmithKlein about what the company is doing to help address global health.
  5. Nigeria moves towards eradication of Guinea worm, Azoma Chikwe, Daily Sun
    After decades of work, Nigeria is on the cusp of becoming another deworming success story.
  6. UNICEF And Partners Kick Off Fifth Annual Global Immunization Meeting, Medical News Today
    UNICEF, the WHO, and the GAVI Alliance are meeting in Geneva to analyze and improve immunization efforts globally

GlaxoSmithKline Launches New “Innovation Strategy,” Includes NTDs

January 21st, 2010

In a speech given to the Council on Foreign Relations in New York today, GlaxoSmithKline (GSK) CEO Andrew Witty announced a list of new initiatives he is launching in an effort to demonstrate GSK’s role in helping control and prevent diseases that disproportionately affect the world’s most impoverished populations.

The list includes:

  1. ‘Open Lab’ established with $8m seed funding for new research
  2. 13,500 malaria compounds to be made freely available
  3. New collaborations to share intellectual property for neglected tropical diseases
  4. Pledge to create sustainable pricing model for world’s most advanced malaria candidate vaccine
  5. GSK African Malaria Partnership awards four new grants worth $2.5m

The “Open Lab” will be a research facility at GSK owned offices in Spain, open to up to 60 scientists from around the world.  The scientists will be part of a drug discovery team with $8 million being spent on research and development for new medicines for  diseases of the developing world.

In addition, GSK is also working with BIO Ventures for Global Health (BVGH) to create a “knowledge pool” for NTDs. GSK and BVGH have partned with  the Emory Institute for Drug Discovery (EIDD) to help further “open up knowledge, chemical libraries, and other assets in the search for new medicines for neglected tropical diseases.”

In order to create a sustainable  commitment for programs that support research for malaria and NTDs,  Witty also announced a pledge to price GSK’s experimental malaria vaccine at just 5% above cost. This pricing model is to cover the cost of the vaccine, and the small return from it will be reinvested into research and development for GSK’s second-generation malaria vaccines and other vaccines for neglected tropical diseases.  

“We are trying to set the expectation that there will be some return” for creating medicines for poor countries, he said in an interview with Forbes. “If we come out and say it is 0% profit” for the malaria vaccine, there would be no incentive for companies to invest in neglected disease research in the future.”

This is definitely a step in the right direction for the fight against NTDs!

If GSK is able to maintain a long-term, sustainable commitment to NTDs and Malaria, hopefully it will incentive other drug companies to follow suit.