Posts Tagged ‘media’

World Population Day 2010!

July 12th, 2010

Yesterday, July 11th was World Population Day.

According to the United Nations Population Fund Website:

“This year World Population Day highlights the importance of data for development. The focus is on the 2010 round of the population and housing census, data analysis for development and UNFPA’s lead role in population and development.

Reliable data makes a difference, and the key is to collect, analyze and disseminate data in a way that drives good decision making. The numbers that emerge from data collection can illuminate important trends. What striking situation does research reveal in your country? What do the numbers tell you about progress toward meeting the MDGs? Are certain groups getting left behind?”

We encourage you to watch this great video by USAID on why population data matters!

New Drug for Chagas Disease?

July 8th, 2010

By: Alanna Shaikh

Right now, two drugs are approved for Chagas disease, benznidazole and nifurtimox. Count them. 1. 2. Doesn’t exactly insure confidence, does it? Also, as an added bonus, they’re 30 years old, which means that there is plenty of resistance to the drugs. They only work in 60-85% of adults, although, thankfully, they do better on children. It’s clear, though, that in terms of Chagas treatment, there is really nowhere to go but up.

That’s why this press release is such good news. “Merck today announced plans to initiate a Phase II investigational proof-of-concept clinical study to evaluate its oral antifungal agent posaconazole for the treatment of chronic Chagas disease.” (Don’t worry, I’ll translate.)

After spending some quality time with Wikipedia and google. I can tell you that a proof of concept study is what they do to determine that a drug can work. It’s the small, brief, study with carefully selected participants that comes before a bigger clinical trial. So, if posaconazole turns out to be effective in this small study, it will go on to broader testing.

The proposed study will be randomized and placebo controlled. It will test the effectiveness of 60 days of posaconazole treatment in 160 adults in South America.* It will follow the participants for 360 days. They’ll test the participants’ blood for the presence of the parasite that causes Chagas disease.

images.com/corbis

If posaconazole is effective in the proof on concept study, it will go on to full trials. That will mean more participants in more locations, and possibly longer periods of time. However, posaconazole is already on the market for other diseases. It is being used in the US to treat Aspergillus and Candida infections in immunocompromised patients 13 years and older. That means we already have safety data on the drug. We don’t have to do a million studies to see if it has horrible side effects. We just have to find out if it really works for Chagas disease.

So, maybe we’re not too far away from a third drug for Chagas disease. That’s a 50% increase in available treatments. Everybody cross their fingers and knock on wood.

It also makes me wonder – how many existing drugs might work on other NTDs? If there is a drug that works for Chagas already in use, what else might be out there? Are we going to find out that Tamiflu works on encephalitis? Prilosec for elephantiasis? Triclosan for trachoma?

Probably we’re not going to find an NTD miracle cure in the bathroom cabinet. But I am awfully glad for the reminder that pharmaceutical companies are still hard at work seeking treatments, even for neglected tropical diseases.

*This is a great example of drug research done right in the developing world. They’re testing the drug in South America, which is also where the drug will have the most impact. That’s not medical exploitation. It’s responsible testing and responsible medicine.

Alanna Shaikh is an expert in health consulting, writing about global health for UN Dispatch and about international relief and development at Blood & Milk. She also serves as a frequently contributing blogger to ‘End the Neglect.’

Are Parasitic Worms a Root Cause of Global Poverty?

July 7th, 2010

by Eric Zuehlke, editor, Population Reference Bureau

Reposted with Permission

The damaging effects of HIV/AIDS and malaria on individuals, families, and communities in developing countries are well-documented. Public advocacy campaigns highlight the millions of deaths each year that can be prevented through basic immunizations that are taken for granted in developed countries. But did you know that 13 parasitic and bacterial infections, mostly worms and trachoma known as the “neglected tropical diseases,” are the most common afflictions of the world’s poorest people? “Neglected” tropical diseases affect about 1.4 billion people worldwide, mostly in rural areas of developing countries. Unlike AIDS and malaria, they aren’t fatal, but they are disabling, leading to lost income from missed work and lower IQs. A recent post on the Discovery magazine blog highlights recent research from the University of New Mexico that hypothesizes that the prevalence of these parasitic infections is the “most powerful predictor of average national IQ” – more than GDP, literacy rates, and school enrollment. The post questions whether correlation is causation and is skeptical about these diseases having effects on the IQ of entire countries:

“…a link between infections and IQ tells us nothing about whether infected people grow up to be less intelligent, or whether intelligent people are less likely to become infected. Intelligence, after all, could affect one’s understanding of what a disease is, how to avoid it, and how to seek help for an infection.”

I think the author misses the point here. The issue isn’t that intelligence may lead to greater knowledge and prevent infection. How does intelligence help in seeking treatment in the poorest rural areas in the world, with little or no medical care or resources to treat these diseases? In addition, lower IQs can have huge lifelong ramifications in terms of educational attainment and employment. Young children are often afflicted by these conditions, delaying mental and cognitive development. A wide body of research has shown that deficiencies in the first years of life have lifelong effects. Nutrition shortfalls have also proven to detrimentally affect IQ. For example, deficiency in iodine, an element that we take for granted in the United States, can lead to impaired cognitive development and is the leading cause of mental retardation worldwide. Given the sheer prevalence and disabling nature of these diseases, you would think there would be more discussion of their effects on productivity, economic development, and social stability. They are a major hidden root cause of poverty. Of course, lack of education and employment opportunities, weak markets for goods and foods for poor farmers, trade imbalances, and conflict over scarce resources are all major contributors to poverty, but without a foundation of good health, how can the other issues be overcome?

I recently interviewed Dr. Peter Hotez, research professor and the chair of the Department of Microbiology, Immunology, and Tropical Medicine at George Washington University about the effects of these diseases on economic development and the interesting potential for “vaccine diplomacy.” He’s also the president of the Sabin Vaccine Institute, an organization working to reach the millions of people affected by neglected tropical diseases. A “rapid impact package” of drugs that eliminate the seven most common tropical diseases can be administered for just 50 cents a person per year. Whether or not the neglected tropical diseases are the single “most powerful predictor of national IQ,” they are a major contributor to poverty.

Eric Zuehlke is a writer and editor at the Population Reference Bureau

Reading List 6/14/2010

June 14th, 2010

A new list of reads to start off your week! Last week, the Global Network hosted a Congressional Briefing on NTD control – check out a synopsis from VOA News (linked below). Also on today’s reading list, global commitment to eliminate elephantiasis, aid workers’ return to Haiti, and the role of scientists in vaccine development.


Researchers, USAID Seek More Money To Fight NTDs, Nico Colombant, VOA News
Global Health Partnership on Track to Eliminate Elephantiasis by 2020, PR Newswire
Wounded Carroll County Aid Workers Return to Haiti, Nick Madigan, The Baltimore Sun
Researchers are out of race for the top job, Financial Times

Dr. Peter Hotez’ interview with EarthSky

June 7th, 2010

Dr. Peter Hotez, President of Sabin Vaccine Institute and Distinguished Researche Professor at The George Washington University, was recently interviewed by EarthSky, a science news outlet that receives 15 million hits a day via radio and online. In the interview, Dr. Hotez discusses the presence of NTDs in the United States, and how similarly in developing countries, the poorest populations are most affected by these debilitating diseases. Check out audio and accompanying synopsis from the intriguing interview, posted on EarthSky’s website.

Reading List 6/3/2010

June 3rd, 2010

We hope everyone’s had a great week so far! We have a brand new list of reads for your daily dose of NTD and global health news. Today we’re reading about a review of studies on the effectiveness of infectious disease programs in developing countries, the Malaysian ministry of health’s focus on infectious diseases, information about The Global Health Progress (GHP) initiative, and dengue in Key West, FL with a mention of Dr. Peter Hotez and his New York Times op-ed.

I found TropIKA’s post on an infectious disease program review to be especially interesting. The post highlights an article where researchers conducted a review using MEDLINE and Science Direct databases to search for studies on infectious disease programs in low-income countries. The findings of the review heavily relied on the terms that were used to search on the databases. One “problem” term in particular includes “pro-poor,” which does not have a clear definition. In fact, findings were limited because of the term’s lack of definition. I found the emphasis that’s put on this term fascinating; it reminds me of how the word “neglected” has been attached to NTDs and how certain words can have such a significant effect on public health. Hope you enjoy the post as much as I did!

Do the poor benefit from infectious disease programmes?, Paul Chinnock, TropIKA
Health Ministry to focus research on four diseases, Tan Yi Liang, The Sun
Improving Access to Healthcare in the Developing World, Mark Grayson, Article Alley
Dengue Virus Infections Linked to Key West, Florida, Mary Ann Liebert, Inc.

Reading List 6/2/2010

June 2nd, 2010

Lots of interesting happenings in the world of NTDs and global health on this warm Wednesday! Today’s reading list includes the launch of a new campaign to fight against Elephantiasis in Sierra Leone, the announcement of a $3 million research grant for schistosomiasis studies in western Kenya, World Vision’s provision of water pumps in Niger, and last but not least, a blog post about foreign aid provided by the U.S. Enjoy!

Campaign against Elephantiasis in Sierra Leone, Bampia Bundu, Awareness Times – Sierra Leone
UGA prof gets $3M to study schistosomiasis, Atlanta Business Chronicle
World Vision Gives Succor to Niger, Provides Clean, Safe Water, Success K. Uchime, All Voices
Restoring U.S. foreign aid to health, Members of the Steering Committee of the Global Health Technologies Coalition, The Hill’s Congress Blog

Reading List 6/1/2010

June 1st, 2010

We hope everyone had a great holiday weekend! To welcome you back and to get your week started off right, we’ve compiled a brand new reading list for your reading pleasure. Today we’re reading about advances in dengue research, high rates of elephantiasis in Bombali, rotavirus vaccines and children’s health, and intestinal worms in swine.

NanoViricides Reports Efficacy in Initial Studies on Dengue Virus, The Wallstreet Journal
Bombali has highest Elephantiasis, Donstance Koroma, Sierra Express Media
Rotavirus vaccine reduces hospitalizations for kids, Thomas Maugh, Los Angeles Times
Brazil suspends processed meat exports to U.S., Reuters

Reading List 5/27/2010

May 27th, 2010

Hope everyone’s had a great week so far! Here’s a reading list to get an early start to your Memorial Day weekend. Today we’re reading about the link between lymphatic filariasis and malaria, the World Bank’s approval of more than $63 million for the creation of a network of public health laboratories in East Africa, and the effectiveness of drug cocktails to treat HIV. We’ve also included TropIKA’s blog post about Dr. Peter Hotez’s recently released 8-point “manifesto” paper. Enjoy the reads!

Drains Linked to Lymphatic Filariasis and Malaria, Science Daily
World Bank Approves $63.66 Million for Lab Network in East Africa, Green TMC
Drug cocktails cut couples’ HIV transmission risk, Reuters
A “manifesto” for combatting NTDs, Patrick Adams, TropIKA

Anyak vs. the Guinea Worm

May 24th, 2010

Anyak vs. The Guinea Worm

Check out this amazing video op-ed by Nicholas D. Kristof from The New York Times. Meet Anyak, a young Sudanese boy who is infected by a guinea worm. He lives in a remote area of Sudan where clean water is not easily accessible, which is a contributing factor in his contraction of the water-borne parasite. Follow his journey as he receives treatment from the Carter Center by way of a campaign called The South Sudan Guinea Worm Eradication program; this village-run program will bring our global community that much closer to eradicating this painful disease, leaving the world free of guinea worms for good.