Posts Tagged ‘plos medicine’

Eliminate the Neglect: U.S. Support Needed to Expand Assault on Neglected Diseases

July 8th, 2011

Sabin Vaccine Institute President Peter Hotez co-authors a guest post with Bernard Pecoul on the PLoS Medicine blog today. The piece highlights the first-ever NTD meeting of the International Society for Infectious Diseases:

“If you asked the average American if they’ve ever heard of sleeping sickness, river blindness, or elephantiasis, you’d likely get a puzzled look. But ask a Congolese, Sudanese, or Bangladeshi about these parasitic diseases, and you might get a nod of the head or perhaps even a point in the direction of someone behaving erratically and slipping into a coma due to sleeping sickness, being led by stick by a child because of river blindness, or barely able to walk due to grossly swollen legs or genitalia caused by elephantiasis.

This weekend in Boston, health workers, researchers, donors, and social innovators from around the world will convene to discuss current efforts to treat patients and develop new drugs and vaccines for neglected tropical diseases (NTDs) such as these. Most of us have never heard of these diseases, although they are the most common infections of the world’s poor, debilitating or killing more than 1 billion people in the developing world.”

Read the full blog entry here.

Reading List 6/30/2010

June 30th, 2010

New list of reads to help get you through the week! Today we’re reading about great strides and advances in the control and elimination of NTDs – such as the substantial drop in human African trypanosomiasis cases over the last five decades – as well as other developments that pose more as obstacles, such as the re-emergence of Dengue in the U.S. Take a look:

Human African trypanosomiasis: number of new cases drops to lowest level in 50 years, WHO
Community-Based Education Strengthens Elimination of Lymphatic Filariasis, Science Daily
Pharmacy students work to close the gap, Charles Sturt University
Foreign Policy Examines GHI, PEPFAR, Kaiser Family Foundation
Researchers In Australia Make Important Malaria Breakthrough, Government of Australia
Do Parasites Make You Dumber?, Cassandra Willyard, ScienceNOW
Dengue Re-emerges in U.S., Spurring Race for Vaccine, Gayathri Vaidyanathan, The New York Times

A Sea of Numbers – Measuring Global Health

June 14th, 2010

Photo Courtesy of http://www.christianwolff.com/Evidence_Based_Treatment.html

By: Eteena Tadjiogueu

There’s a sea of numbers and figures to sift through when trying to measure impact and need in the global health arena. If you dare, you can try to figure out a nation’s disease burden for a specific infection, the rate of mortality and/or morbidity, population size, resources and infrastructure, etc. If you can find what you’re looking for, there still remains a need to connect the dots between the various data, and often times, various sources.

The theme of the 2010 Global Health Council conference—which begins today in Washington, DC—is “Global Health: Goals & Metrics.” The conference is calling attention to a great need and opportunity for global health practitioners to collect and distribute accurate and informative figures that will impact funding for NGOs, and research and development of medications and vaccines if the need exists (which, of course, it does).

So where should you look if you’re interested in learning more about a specific global health problem? For starters, all things NTDs are found on the Global Network for Neglected Tropical Diseases’ site, in particular the interactive map holds a wealth of information on NTDs and stories from the field. If you don’t have access to an academic research system like LexisNexis, then you should check out the Public Library of Science which is an open-access (ie. free) scholarly journal that frequently features editorials from the Sabin Vaccine Institute’s President, Dr. Peter Hotez, as well as other notable scientists and researchers. Sabin.org has information on NTDs and diseases like rotavirus, HPV, and pneumococcal disease. When I’m looking for vaccine specific data I sift through the country data from the GAVI Alliance and the World Health Organization.

One of the Pneumococcal Awareness Council of Experts’ members, Hans Rosling, has created one of the most well known and visually appealing statistic aggregators. If you haven’t heard of Gapminder then I encourage you to take a look. Here you’ll find a list of indicators which come to life when you click play. Gapminder doesn’t currently have any information on NTDs, which is unfortunate, but their a step ahead of most in recognizing the great need for global health and development data and for making their “graphs” free and easy to understand.

What are some of your favorite sources for global health statistics and data?

Innovative financing for neglected diseases

May 26th, 2010

Reprinted with permission from: The Global Health Blog – a project of PubHealth.org

By: Sarah Arnquist

List of NTDs

List of NTDs

Neglected tropical diseases attracted the media spotlight this month, starting with a New York Times op-ed by Peter Hotez, president of the Sabin Vaccine Institute.

Now, Hotez and Bernard Pecoul, executive director of Drugs for Neglected Diseases initiative (DNDi), have released a “manifesto” outlining why the global community should increase financial support for NTD control, elimination efforts and research and development.

“About three-quarters of total neglected disease R&D annual spending is for HIV/AIDS, malaria, and tuberculosis, leaving only about US$600 million worldwide for all NTDs per year,” they write.

Last week, the open-access journal, PloS Medicine, hosted a debate over the best approach to tackle neglected tropical diseases. (For a quick overview read the blog post, “Neglected diseases: teach or treat?” from The Scientist.) The debate centered on whether the focus to eliminate the diseases has been overly medicalized at the expense of focusing on social determinants of disease and how future resources and investments should be best allocated to balance implementation and R&D.

The debate and dialogue are great and necessary, but calls for any additional funding, regardless of how it’s allocated, begs the question where will the money be raised.

While global health experienced a “golden age” of new financial commitments during the last decade, international development assistance for health has flat-lined. Given the plurality of funding demands, including HIV prevention and treatment, chronic diseases, trauma and injury and neglected tropical diseases, many say merely sustaining — let alone expanding — financial assistance requires new “innovate financing” models for global health.

Innovative financing examples include:

  • UNITAID — an international fund that uses revenues from taxes on airline tickets to promote lower prices and improved access to drugs, bed nets, etc.
  • Advance Market Commitments (AMCs), in which legally binding commitments to pay for new life-saving vaccines aim to stimulate faster and larger industry investments in R&D.
  • International Financing Facility (IFF) — rich country governments make long-term pledges to collateralize commercial debt financing.
  • Debt Swaps – rich country creditors write off debts owed by developing countries if they convert a portion of the debt value to disease control activities.

Sarah Arnquist is the editor of The Global Health Blog, part of PubHealth.org, a project aimed to create an online mechanism to facilitate harmonization among international health care researchers, practitioners and funders. Arnquist writes case studies on global health delivery issues and previously worked as a journalist. She has a master’s in public health from Johns Hopkins School of Public Health.