Posts Tagged ‘R&D’

Night 8: The “Other” NTDs

December 19th, 2009

Tonight we’ll wrap up our Hannukah and NTDs series with a focus on the remaining NTDs as defined by the WHO: buruli ulcer, dengue fever, guinea worm, African sleeping sickness, leishmaniasis, and leprosy.  At the Global Network, we are commonly asked “why do you only focus on seven NTDs?”  The seven NTDs we’ve detailed over the last seven nights are the most common NTDs, representing approximately 90% of the total disease burden.  We also focus on them, however, because they are generally referred to as “tool-ready”–that is to say, we have medications that are safe, affordable, and available to treat the seven most common.

Which brings us to the “other” NTDs that also cause significant suffering among the poorest of the world’s communities. Like the most common ones, these NTDs promote the continuation of poverty in developing communities by impairing physical and intellectual growth and decreasing worker productivity.  But unlike the others, they are either missing treatment/control tools altogether or the tools are difficult to access or afford.

Many groups are working to change this landscape.  Analysis from Drugs for Neglected Diseases initiative (DNDi) clarifies:

For the “most neglected” diseases, patients are so poor that they have virtually no purchasing power and cannot spark market interest in drug R&D among pharmaceutical companies. Recently, the field of R&D for neglected diseases has seen the emergence of several new organisations, new donors, new financial mechanisms, and a new political environment. However, although the global R&D landscape has improved for neglected diseases since 2003, the dire needs of the most neglected victims who carry on suffering in the developing world are still largely unmet. A recent study by G-Finder revealed that less than 5 percent of worldwide R&D funding for neglected diseases has been directed towards the most neglected diseases.

To read more about these NTDs, visist our website.

Health Affairs Briefing Focuses on NTDs

November 3rd, 2009

The Global Network team just returned from a half-day briefing hosted by the health policy journal Health Affairs, initiated around their November/December 2009 Issue focused on neglected diseases.  The event spurred fascinating dialogue on the current burden of NTDs around the world, control efforts underway, broad partnerships engaged on the issue, and the work ahead.

A wide range of experts presented throughout the morning, including:

  • Philip Musgrove and Peter Hotez, who gave thorough overviews on the current NTD situation and ongoing advocacy, policy, resource mobilization, and control/elimination efforts.  Specifically, they discussed the world’s massive NTD burden, the growing shift toward innovative and flexible regional control strategies, the mobilization of communities to deliver integrated interventions, and the importance of the Obama Administration’s Global Health Initiative and its inclusion of NTDs as a key pillar.
  • Ken Gustavsen, Christy Hanson, Joseph Damond, and Scott Ratzan, who discussed the immense value of public-private partnerships engaged in the field of NTDs.  The drug donation programs of major pharmaceutical companies–Merck, Pfizer, and Johnson & Johnson–were highlighted, as were their commitments to innovation, scalability, and sustainability.  USAID’s NTD program was also detailed, including their commitment to building on existing health platforms and to working with affected communities.
  • Peter Singer and James Geraghty, who discussed what else needs to be done for these diseases.  Singer outlined a new “global acceleration plan” to support developing world pipelines for innovation–a potential “goldmine” for new NTD technologies.  Geraghty advocated for expanding the biotech industry’s involvement in fighting neglected diseases but also working to improve incentives–through mechanisms such as tax credit legislation advocated for by Genzyme–for companies to do so.
Dr. Peter Hotez presents at the Health Affairs Briefing

Dr. Peter Hotez presents at the Health Affairs Briefing

» Read more: Health Affairs Briefing Focuses on NTDs