All posts by Anjana Padmanabhan

About Anjana Padmanabhan

Anjana Padmanabhan is a communications officer and manages all the social media accounts for the Global Network for Neglected Tropical Diseases including the "End the Neglect" blog.

“Human Time Bomb for Mosquitoes”

Echoing several articles published last week, Donald McNeil Jr. of the New York Times also shed light on the recent study conducted in the American Journal of Tropical Medicine and Hygiene by scientists from Senegal and Colorado State University.

As mentioned previously, the study demonstrated that ivermectin, a drug used to treat onchocerciasis, can also kill mosquitoes.

Scientists such as Dr. Peter Hotez, President of the Sabin Vaccine Institute, are enthusiastic about this study’s effects on combating malaria and other mosquito borne illnesses, however, the article also provided some cautious perspectives from others. For the drug to effectively kill mosquitoes, nearly everyone in an infested area would need to take the pill simultaneously. In addition, the mosquito killing effects fade after a month so ivermectin, which is typically only distributed once or twice a year to a community, would need to be distributed more frequently.

The article goes on to say, “Also, when people with lots of worms are treated, they suffer fever and intense itching as the worms die. Though that might be bearable once a year, it discourages people from seeking treatment more frequently. And ivermectin is dangerous for a few people — those infested with large numbers of a relatively rare West African worm, the loa loa. These worms circulate in the blood and lungs and may jam capillaries when they die, potentially causing coma or death. Detecting them means drawing blood and viewing it under a microscope.”

Read the full article here

Drug Used to Treat River Blindness Could Reduce Malaria Transmission

A new study published in the American Journal of Tropical Medicine revealed that ivermectin, which is used to treat onchocerciasis (also known as river blindness) can also interrupt the transmission of malaria.

From an article on the study:

“The study by scientists from Senegal and Colorado State University found that transmission of malaria parasites by mosquitoes fell substantially among people living in several Senegalese villages over two weeks after they took the drug ivermectin, which was administered as part of a campaign to fight the parasitic roundworm that causes onchocerciasis, or river blindness. The drug appeared to kill malaria-carrying mosquitoes that fed on the blood of the villagers.”

Dr. Peter Hotez, President of the Sabin Vaccine Institute was also quoted in the article saying, “This study offers good news on several fronts, not the least of which is the potential to disrupt the transmission of malaria and save needless suffering and death. We need more creative science like this that has simple yet powerful results in our battle against neglected diseases of poverty. In terms of river blindness, this drug has transformed lives, said Hotez. “To add malaria to its already impressive return on investment would be an incredible development.”

Treating both NTDs and malaria simultaneously is cost-effective and will save many more lives in the long run. To find out how you can help the distribution of ivermectin and other drugs to treat NTDs for just 50 cents, please visit our Get Involved page.

Science magazine also had a write up on the study mentioning the work of the Global Network. The article quotes Dr. Hotez saying, “We’re only beginning to understand the enormous potential impact of MDAs on diseases for which they weren’t intended.”

WHO research programme on tropical diseases wins Gates Award

The Special Programme for Research and Training in Tropical Diseases (TDR), based at WHO headquarters in Geneva and co-sponsored by UNICEF, UNDP, the World Bank and WHO, has won the 2011 Gates Award for Global Health.
TDR which has been operating since 1975, has supported and advocated for research and development to address infectious diseases and has had a major impact on reducing the burden of onchocerciasis, dengue, malaria, Chagas’ disease and visceral leishmaniasis .TDR will recieve $1 Million as a part of the reward which will go to expanding its fellowship and training programs.

Read the full press release here

The True Size of Africa

Came across this awesome infographic via GOOD. Click on the image to view it larger.

In addition to the well known social issues of illiteracy and innumeracy, there also should be such a concept as “immappacy,” meaning insufficient geographical knowledge.

A survey of random American schoolkids let them guess the population and land area of their country. Not entirely unexpected, but still rather unsettling, the majority chose “1-2 billion” and “largest in the world,” respectively.

Even with Asian and European college students, geographical estimates were often off by factors of 2-3. This is partly due to the highly distored nature of the predominantly used mapping projections (such as Mercator).

A particularly extreme example is the worldwide misjudgment of the true size of Africa. This single image tries to embody the massive scale, which is larger than the USA, China, India, Japan, and all of Europe … combined!