Tag Archives: pharmaceuticals

Strengthening Supply Chains for NTDs through Partnerships

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Have you ever been curious about how the medicine to treat neglected tropical diseases (NTDs) reaches communities across the world? A new from GlaxoSmithKline (GSK) explains how establishing key partnerships and implementing evidence-based supply chain methods enables us to prevent and treat those that are suffering from NTDs across the globe.

Through the 2012 London Declaration on NTDs, pharmaceutical companies, non-governmental organizations (NGOs), and donor and endemic governments dedicated themselves towards scaling up drug supply to over a billion people suffering from NTDs. In 2013, 1.35 billion low-cost treatments for NTDs were donated to more than 70 endemic countries worldwide.

To build upon the successes realized over the past two years and to meet the NTD control and elimination goals by 2020, new approaches on the methodology of supply chain management for NTDs are needed. To answer this challenge, pharmaceutical industries, NGOs and supply chain experts formed the NTD Supply Chain Forum. The team includes pharmaceutical companies (GSK, Pfizer, Eisai, Merck Serono, J&J, Merck & Co., Inc), NGOs (Children Without Worms, International Trachoma Initiative  Mectizan Donation Program), DHL, JSI, and Bill & Melinda Gates Foundation.

Their goal is to simplify complex logistical, manufacturing, and personnel challenges to streamline the high number of drugs being distributed to rural villages, schools, and clinics in need of NTD treatments.

Already through this partnership, 809 million treatments were donated for lymphatic filariasis, 115 million treatments for onchocerciasis, 276 million treatments for soil transmitted helminthes, 52 million treatments schistosomiasis and 51 million treatments for trachoma.

We encourage you to watch GSK’s video on . For more information about the supply chain progress that is being made for NTDs, please read the Supply Chain section of the recent 2013-2014 report on Delivering on Promises & Driving Progress: The Second Report on Uniting to Combat NTDs.

Join the Conversation: Pharmaceuticals and Partnerships in the Fight Against NTDs

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Photo by Mo Scarpeli

Photo by Mo Scarpeli

Recently, Dr. Neeraj Mistry, Managing Director for the Global Network, joined the Pharmaceutical Research and Manufacturers of America (PhRMA) for an online conversation about neglected tropical diseases (NTDs).  He was joined by industry and NGO leaders in highlighting the importance of innovative partnerships and the vital role of pharmaceutical companies in fighting these diseases.

“Over the past year, we have seen some encouraging signs of progress from regional and national bodies in NTD-endemic regions,” Dr. Mistry said.  “Thirty-six African nations have developed multi-year national plans to control and eliminate NTDs by 2020. Also, at WHO’s 63rd Regional Committee for Africa, countries adopted a regional strategic plan recommending increased access to treatments, resource mobilization, advocacy, and monitoring and evaluation, surveillance and research.  In the past several months, the World Health Assembly, Organization of American States and African Union have all adopted resolutions against NTDs and strengthen efforts to integrate NTD programs into other health sectors.”

Through large-scale treatment donation, expanded research, increased information sharing and building cross-sector networks, the pharmaceutical industry has demonstrated a long-term commitment to combating NTDs.  AbbVie, for example, is collaborating with foundations and academic institutions to provide a library of chemicals to screen against NTDs, while GlaxoSmithKline has partnered with Pfizer and CARE India to research ways to eliminate visceral leishmaniasis.  And Merck now reaches more than 200 million people annually through its innovative, multi-sector Mectizan Donation Program, which focuses on combating onchocerciasis and has been expanded to include treatment for LF.

But the fight is not yet over, and the pharmaceutical industry is just one part of a diverse group of stakeholders – from NGOs and policymakers to industry and academic institutions – leading the charge against NTDs.  “Funding is being mobilized, but more is needed.  The capacity to deliver treatments in some countries needs strengthening.  New diagnostics are needed to better understand when to start and stop treatments.  For some diseases, new and better drugs or treatment strategies are needed to fill gaps where current therapies are limited or lacking.  Endemic country governments need the political will and resources to address NTDs in their countries,” noted Brenda Colatrella, Merck’s Executive Director of Corporate Responsibility.

Through collaboration, innovation and sustained commitment, these partners can, and will, continue to make progress toward control and elimination of these diseases.

To read the entire conversation, click here.

Top five ways Big Pharma can address neglected diseases

NTDs, pharmaceuticalsForbes, ,

Forbes contributor Sarika Bansal continues her discussion on Big Pharma’s role in combating NTDs. Take a look at her previous post, and read an excerpt of her current post:

“My last post discussed the reasons why neglected diseases have historically been neglected, the growing efforts to eradicate them, and why pharmaceutical companies should develop more drugs for them. Unfortunately, the traditional economics of drug development are stacked against neglected diseases, which disproportionally affect the world’s poorest populations. Drug development is a costly and time-consuming process, and even if a pharmaceutical company did develop a viable drug for a neglected disease, they would have virtually no way of recouping their investment.” Click here to read the full blogpost.

How pharmaceutical companies can help take the “neglected” out of NTDs

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Forbes contributor Sarika Bansal wrote a piece highlighting NTDs. Published today on Forbes, Bansal gives an overview of the problem, and offers a solution that involves more investment from the pharmaceutical industry. Read an excerpt below, or click here to read the full article which mentions the Global Network, the Sabin Vaccine Institute and its President Dr. Peter Hotez:

“What do schistosomiasis, cysticercosis, and lymphatic filariasis have in common?

Besides verging on the unpronounceable, they are all classified as neglected tropical diseases (NTDs). NTDs are a set of diseases – seventeen, by the World Health Organization’s count – that collectively affect over a billion people, but have historically received little attention. The most common NTDs, including those listed above, are caused by parasitic worms or protozoa. Others, such as leprosy and trachoma, are the result of bacterial or viral infections.

Though caused by a range of pathogens, NTDs share some important characteristics. First, many are diseases of rural poverty. Most neglected diseases affect the poor in the developing world, particularly in Africa and Asia, but some have also been found in “pockets of poverty” in the United States. For instance, hundreds of thousands of Americans, most of whom are Hispanic immigrants, suffer from Chagas disease. Second, most NTDs cause bodily impairment and disability (i.e., they have high morbidity) but are not very lethal (i.e., they have low mortality).”