Tag Archives: Schistosomiasis

Merck Serono Helps Eliminate Schistosomiasis in Africa

Merck Serono plans to double its donation from 25 million tablets to 50 million tablets and will continue a commitment to donations indefinitely, until schistosomiasis has been eliminated in Africa. In a press statement released today, Merck Serono said that in addition to doubling their annual donation of praziquantel, they will financially support a World Health Organization (WHO)-led school-awareness program in Africa aimed at preventing the occurrence of schistosomiasis.

“Together with WHO, we want to help to successfully fight this insidious tropical disease,” said Stefan Oschmann, Executive Board Member of Merck KGaA and President of Merck Serono.

You can read more about Merck Serono’s commitment to eliminate Schistosomiasis in their press release, linked here.

Schistosomiasis Reemergence in China

For the past five decades, China has been successful in controlling schistosomiasis in endemic areas. Through snail control, chemotherapy, health education, and access to clean water the disease was eradicated in three provinces, in Shanghai, and in the Guangxi Province. In Sichuan at the end of 2004, however, schistosomiasis reemerged in seven counties where disease transmission was previously controlled.

Schistosomiasis is a neglected tropical disease that is spread to humans by contact with snail-infested waters. These snails are infected with the parasite Schistosoma and live in fresh water. In Sichuan, China the disease was first documented in 1924; however, it wasn’t until 1985 that transmission control was achieved in 20 counties, then increased to 21 counties in 2001. Reemergence of schistosomiasis in seven  of these counties may be attributable to sociopolitical, economic, environmental, and surveillance system changes, including:

  • decreased funding for health workers
  • decreased awareness of the issue among the local government and lack of coordination between government departments (public health, agricultural, husbandry departments, for example)
  • increased establishment of snail habitats (creation of irrigation canals, for example)
  • ineffective surveillance systems post-control of the disease

To regain control of schistosomiasis transmission, researchers call for a combination of chemotherapy, snail control, and improvements in sanitation. Increased funding in environmental modification and rural sanitation would also attribute to getting transmission under control.

Before solutions are implemented, however, several considerations must be taken into account. Transmission of the disease varies from area to area. In mountainous regions, snails infected with the Schistosoma reside in the irrigation canals on farms, which make farmers the most vulnerable population for contacting the disease. In other areas where the infected snails inhabit lakes and marshlands, bovine are largely responsible for transmission. Because of differing transmission cycles, it is important to develop solutions that are generalizable over a variety of regions. Also, looking toward inter-sectoral funding where resources can come from departments outside the ministry of health such as those that govern energy, water, agricultural, and animal resources will also help health officials regain control of schistosomiasis in Sichaun.

Reading List 10/25/2011

Stay up to date on the latest NTD and global health news with our reading list! Today we’re reading about:

Pfizer Donates Zithromax, Promotes Eye Screening
AS part of its corporate social responsibility and efforts to forestall the onset of preventable eye disorders such glaucoma and trachoma which lead to blindness, Pfizer Specialities Nigeria recently held free eye screening services in Abuja, Ilorin, Kano, Osun, Akwa-Ibom and Delta States. A donation of Zithromax was officially handed to the Minister of Health in Abuja through the company’s International trachoma Initiative.

Global plan targets devastating eye disease
Blinding trachoma, one of the oldest known infectious eye diseases, may be facing its end game. The world’s leading cause of preventable blindness, trachoma brings extraordinary human suffering and economic devastation to tens of millions of people, mostly women and children in poorer countries. Yet as a result of development and targeted interventions it is now limited to an estimated 59 countries, often affecting the poorest populations in Africa and Asia.

5 districts declared filariasis disease free
Dhaka, Oct 25 (bdnews24.com) – The government has declared five districts free of the crippling mosquito-borne filariasis disease, for the first time in Bangladesh after years of mass drug administration. State minister for health Mozibur Rahman Fakir, on Tuesday, announced the name of the districts – Meherpur, Rajshahi, Dinajpur, Patuakhali and Barguna – where the prevalence rate for the parasitic disease, also known as elephantiasis, was found to be below one percent.

A Fresh Insight into Transmission of Schistosomiasis: A Misleading Tale of Biomphalaria in Lake Victoria
Lake Victoria is a known hot-spot for Schistosoma mansoni, which utilises freshwater snails of the genus Biomphalaria as intermediate hosts. Different species of Biomphalaria are associated with varying parasite compatibility, affecting local transmission. It is thought that two species, B. choanomphala and B. sudanica, inhabit Lake Victoria; despite their biomedical importance, the taxonomy of these species has not been thoroughly examined.

Economics of drug discovery, development for neglected diseases
One of the major reasons why some of the major healthcare problems related to neglected diseases are not addressed by large pharma companies is the lack of large markets which are enablers for ensuring adequate returns on the investments made. For example with rising costs of drug discovery reaching over $ 1.5 billion for every new drug reaching the market, there are not many drugs for neglected diseases which could attract adequate markets in value terms.

Reinventing the Toilet

New innovations in water sanitation and waste management can make great strides in NTD prevention, especially in diseases such as trachoma, schistosomiasis, and onchocerciasis which can be caused by contaminated water. Check out this video released by the Bill and Melinda Gates Foundation about new innovations in water and waste infrastructure.