Posts Tagged ‘ivermectin’

Drug Used to Treat River Blindness Could Reduce Malaria Transmission

July 7th, 2011

A new study published in the American Journal of Tropical Medicine revealed that ivermectin, which is used to treat onchocerciasis (also known as river blindness) can also interrupt the transmission of malaria.

From an article on the study:

“The study by scientists from Senegal and Colorado State University found that transmission of malaria parasites by mosquitoes fell substantially among people living in several Senegalese villages over two weeks after they took the drug ivermectin, which was administered as part of a campaign to fight the parasitic roundworm that causes onchocerciasis, or river blindness. The drug appeared to kill malaria-carrying mosquitoes that fed on the blood of the villagers.”

Dr. Peter Hotez, President of the Sabin Vaccine Institute was also quoted in the article saying, “This study offers good news on several fronts, not the least of which is the potential to disrupt the transmission of malaria and save needless suffering and death. We need more creative science like this that has simple yet powerful results in our battle against neglected diseases of poverty. In terms of river blindness, this drug has transformed lives, said Hotez. “To add malaria to its already impressive return on investment would be an incredible development.”

Treating both NTDs and malaria simultaneously is cost-effective and will save many more lives in the long run. To find out how you can help the distribution of ivermectin and other drugs to treat NTDs for just 50 cents, please visit our Get Involved page.

Science magazine also had a write up on the study mentioning the work of the Global Network. The article quotes Dr. Hotez saying, “We’re only beginning to understand the enormous potential impact of MDAs on diseases for which they weren’t intended.”

Venezuela Interrupts Transmission of Onchocerciasis in North-Central Region

June 3rd, 2011

Venezuela has successfully interrupted the transmission of onchocerciasis in the north-central region of the country. Using its National Onchocerciasis Elimination program, the country distributed ivermectin throughout the region over a course of seven years (2003-2007). The program was implemented with the goal of interrupting transmission within the region by 2012. Read more about this breakthrough in the fight against NTDs on the Pan American Health Organization’s (PAHO) website.

Photo Courtesy of PAHO

Elimination of lymphatic filariasis: do we have the drugs to complete the job?

December 20th, 2010

2020 is the deadline that the WHO Global Programme to Eliminate Lymphatic Filariasis (GPELF) set to eliminate lymphatic filariasis (LF). Currently LF is treated through mass drug administration (MDA) – which is administering drugs to an entire population to treat a diseases -  using diethylcarbamazine or ivermectin monotherapy, or either drug in combination with albendazole. However, over the past five years of MDA, transmission of LF has yet to be interrupted. Other issues that have arisen include development of adverse health effects (specifically the onset of Loa loa) associated with consumption of the current drugs used for treatment. Moses J. Bockarie and Rinki M. Deb of the Liverpool School of Tropical Medicine recently published an article reviewing the current state of LF elimination. Read the full article here.

Reading List 11/15/2010

November 15th, 2010

Happy Monday readers! New list of reads for your reading pleasure. Today we’re reading about how the discovery of how the drug Ivermectin works could possibly lead to the development of other treatments for infectious diseases, a report released by the International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) stating drug makers’ commitment to developing medicines and vaccines for various neglected tropical diseases (NTDs) among other diseases, the disease burden attributed to lack of water sanitation and poor hygiene – part 1 of a series by PLoS Medicine, and lastly how poor hand-washing has lead to the spread of typhoid in Indonesia.

How Key Drug Kills Worms In Tropical Diseases Discovered By Researchers, Medical News Today
Hygiene, Sanitation, and Water: Forgotten Foundations of Health, PLoS Medicine
Report Documents Increase In R&D Projects On Developing World Diseases, Medical News Today
Poor Hand-Washing Habits Blamed for Spread of Typhoid. Dessy Sagita, Jakarta Globe